New antibiotic follows "Trojan horse" strategy to kill bacteria



[ad_1]

Trojan horse

Source image
Getty Images

Legend of the image

Scientists are working on more tests on the antibiotic that uses the "Trojans" strategy

Scientists have developed an antibiotic that can be very effective at treating bacteria in the early stages of infection.

The new antibiotic, developed by the pharmaceutical company Xiongyi, is based on the idea of ​​a "Trojan horse" in the well-known Greek myth, which deceives bacteria and infiltrates them.

The new treatment was tested on 448 cases of kidney and urinary tract infections, which proved effective after ingestion.

The drug experts said the results were encouraging for the development of the new drug, described as "promising".

Safe and good

The researchers, who developed the new antibiotic, inspired the idea of ​​a Greek legend referring to the huge wooden horse in which Greek warriors hide to deceive the enemy in the city of Troy.

But they replaced the wood with an iron element in the body, as a trick to introduce the antibiotic into the bacteria.

"In acute infections, the body creates an iron-poor environment, which constitutes an innate immune response to bacterial resistance, which increases the absorption of iron," said Simon Portsmouth, the head of the department. research team who developed the new drug.

The new antibody, called spidirocol, combines with the iron in the body, causing the bacteria to make a fatal mistake after passing the drug into areas beyond its defenses and infiltrating and killing its cells.

The scientific journal Lancet published the results of research on which the new drug was developed.

"Spidirocol has proven effective in its treatment," Portsmouth said.

The new study is rare in this area because bacteria are immune to antibiotics, resulting in infection levels that are difficult to treat in some cases.

Antibody resistance

The Antimicrobial Antimicrobial Review report indicates roughly that about 10 million patients will lose their lives each year due to a significant increase in the ability of microbes and infectious bacteria to mutate and resist drugs from here 2050.

"This important study gives hope for a new antibiotic that could replace the treatment of infectious bacteria, but the work is not yet complete," said Sergey Mostoy, a professor at the London School of Hygiene and Tropical Medicine.

The new treatment must be further tested for effectiveness and medical effects.

A number of people with acute infections, such as pneumonia, who use carbapenim antibiotics, hope to play a role in obtaining the opportunity to experiment with the new antibiotic.

Once the spidyrocol is infiltrated into bacterial cells, the compound can kill it as effectively as ordinary antibiotics.

Experts said that we badly needed these new types of deadly antibiotics for bacteria.

————————————————– ——————

You can receive notifications on the most important topics after downloading the latest version of the BBC Arabic application on your mobile phone.

[ad_2]
Source link