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Scientists at the American Institute for Cancer Research Dana-Farber have discovered molecular targets in malignant tumor cells for two types of cancer that can not be treated.
According to MedicalXpress, synovial sarcoma is a "rare type of soft tissue cancer typically found in young people" and tumors in children under 2 years old infect the brain, kidneys and other body organs.
The researchers found that the development of synovial sarcoma and tumors in children was due to the reconstitution of chromatin in the ncBAF compound, which governs the activity of several genes and plays an important role in conditioning of chromatin, a chromosome composed of DNA, RNA and proteins.
The researchers also discovered the presence of BRD9 and GLTSCR1 in the ncBAF compound, unique subunits not present in similar compounds.
Scientists hope their discoveries will help develop new methods of treating synovial sarcoma and pediatric tumors.
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