Allergic reactions may be limited to the first injection – study

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Those who had an allergic reaction to the first dose of the COVID-19 vaccine did not face serious complications upon receiving the second dose, according to a study published Monday in JAMA Internal Medicine.

The peer-reviewed study concludes that those who had a reaction to the first dose should not hesitate to receive the second.

Researchers reviewed the medical records of 189 patients who had allergic reactions to the first dose of the Moderna or Pfizer coronavirus vaccines. Some 159 received a second dose; an antihistamine premedication was administered to 47 patients before their second injection.

All 159 patients tolerated the second dose well.

Those who faced anaphylaxis on the first dose tolerated the second. Thirty-two of 159 reported immediate and potentially allergic symptoms that were mild or resolved with antihistamines alone, the researchers said.

Allergic reactions after COVID-19 vaccines have been reported at around 2%, with anaphylaxis occurring in up to 2.5 per 10,000 people.

Beginning in March, the CDC recommends that you not get a second shot of the vaccine if you have a severe allergic reaction. However, if your reaction was limited to a rash, you should still receive a second dose.



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