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Hair Loss
London, July 30 (EFE) .- A compound tested in mice could reverse hair loss and graying, as well as other skin-related damage to a rich diet. According to a study published today by Scientific Reports
According to research – conducted by the Johns Hopkins University School of Medicine – the mixture would slow down the production of certain fats called glycosphingolipids (GSL) . ), which are found in the skin and other cell membranes.
GSL fats are related to hair loss and other skin damage, as explained by the experts involved in the study.
Their production could slow down with the compound D-PDMP, made with D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol and which was tested in a group of mice.
These findings were after feeding, from 12 weeks to 20 weeks, a group of mice with a Western diet high in fat and cholesterol, and a second group with a standard diet.
In comparison with those who received standard foods, mice with western nutrition lost and suffered graying hair as well as skin lesions.
These results became more severe when mice continued to eat a Western diet for 36 weeks, with 75% of rodents having problems in the hair and multiple skin lesions.
"Our results show that a Western diet causes hair loss and graying and inflammation of the skin in mice. We believe that humans who consume a diet high in fat and cholesterol are living a similar process, "said Dr. Subroto Chatterjee, professor of pediatric medicine at Johns Hopkins University.
The study, funded by the National Institutes of Health, In turn, he showed that when the mice receive the D-PDMP compound, the symptoms are reversed
However, the experts said that this evidence does not mean that the mixture is safe and has the same effect in people 19659004] Despite this, they argue that the study sheds light on the possible ways to curb hair loss and skin damage in humans by topical or oral medications.
"Further research is needed, but our discoveries They promise to one day use a drug against skin diseases such as psoriasis and injuries resulting from diabetes or plastic surgery, "Chatterjee said.
In this sense, previous studies have shown that GSL are present in the cells that form the upper layer of the skin, as well as in the keratinocytes, cells responsible for regulating the pigmentation of the eyes, skin and skin. hair.
how the alteration of the GSL could affect the appearance and color of the skin, as well as guarantee the effectiveness of D-PDMP treatment, would cancel any negative effect.
"We hope that in a day, this could mean greater rapid and effective balding recovery, graying hair in aging populations and healing wounds," said Dr. Chatterjee
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