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By identifying the presence of "4 biomarkers (proteins), a blood test can improve the identification of people at risk of lung cancer in the years to come," say scientists at the International Center for Research on Cancer. cancer (IARC) of WHO in Lyon
These biomarkers "can refine the criteria for inclusion of current and former smokers" in the context of screening programs.
63% of cancers identified [19659003] In collaboration with the University of Texas, scientists badyzed a US cohort to establish a predictive biomarker database. The risk was then evaluated in two European studies. *
By combining the results of the four biomarkers with the smoking data, the scientists were able to diagnose 63% of the cancer cases that will actually occur in the population at risk (smokers and former smokers). This figure is 42% when screening is based on "current US screening eligibility criteria," says Dr. Mattias Johansson, lead author of the study. That is, "people aged 55 to 80 who have smoked a pack of cigarettes for 30 years, whether they are still smoking or have been arrested for less than 15 years". Based on the "low-dose CT" technique, this screening test can "reduce lung cancer mortality by detecting a tumor early."
Note: Lung tumor accounts for 20% of cancer deaths worldwide. "The fight against smoking is the main lever to reduce this incidence. In addition, "exposure to pollution and radon", a colorless and odorless radioactive gas, is the second risk factor for lung cancer after cigarette smoking.
* European Prospective Investigation into Cancer and Nutrition (EPIC) and the Northern Sweden Health and Disease Study (NSHDS)
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Source: Destination Santé
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