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Researchers unveiled on Saturday, July 7th, the encouraging results of an experimental vaccine against AIDS. It is ready for a test phase on more than 2000 people in Africa.
An encouraging progress towards one towards an HIV vaccine. Several researchers, including Harvard University virologist Dan Barouch, presented in the scientific journal The Lancet the results of an experimental vaccine that elicited an immune response in humans and protected macaques from infection. [19659003] The study, published Saturday, July 7, reports the results of a test on 393 adults. All were in good health, HIV-negative and aged between 18 and 50, in East Africa, South Africa, Thailand and the United States. Among these participants, some received one of the possible vaccine combinations, others, a placebo, via 4 injections in 48 weeks. Combinations were made of different types of HIV virus, made sufficiently harmless, in the hope of getting an immune response. This was "robust," says Dan Barouch, study director.
A test of 2,600 women in southern Africa
The tests also showed safety. Only five patients experienced side effects such as abdominal pain, diarrhea, dizziness or back pain. These vaccines were tested in a separate study on 72 macaques. As a result, he protected two-thirds of the animals that were inoculated with the virus.
"These results represent a milestone," says Professor Barouch. The development of this vaccine potential, safe for humans, is sufficiently advanced and will be tested on 2,600 women in southern Africa. The virologist says there is no guarantee that the following tests are so positive. To know the results of this test called Imbokodo (rock in Zulu) it will be necessary to wait until 2021 or 2022.
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