Breast cancer: "detractors of screening are irresponsible"



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At the head of the National Cancer Institute (INCa) for two years, Professor Norbert Ifrah is rare in the media. But critics who swell on bad cancer screening worry and annoy him. In our columns, he gives a warning cry.

In France, less than one in two women participate in organized screening. Is this figure satisfactory?

PROFESSOR NORBERT IFRAH. No, all the less satisfying as we have lost 2% of participation in two years and we are far from the European recommendations that advocate 70%. That a scientific debate exists on the limits of screening is healthy. But we are witnessing in France a campaign of surreal denigration, especially on social networks. Its detractors, few but very active, are irresponsible. Let's not forget that 59,000 new bad cancers are detected every year and that 12,000 women die from it.

In particular, screening is accused of overdiagnosis. Clearly, to detect lesions that would not necessarily have evolved into cancer …

Today, a certain number of localized cancers do not evolve, without one knowing why. It is a major subject of research. But 80% will evolve, hence the need for regular monitoring. I am not saying that there is zero useless operation, but they are very few. On the other hand, we know that with organized screening, we save nearly 12% of women a heavy surgery and that a third "only" will have chemotherapy for more than half off screening. For those concerned, it's not nothing!

But the number of treatments does not decrease with screening!

It does not decrease but does not increase either as the target population increases. We went from 7 million women aged 50 to 74 at the end of 1992 to 9.3 million in 2012. That is more than 35%.

A group of badociations, including Cancer Rose, reproaches the INCa to "misinform" women to fill quotas. What do you answer?

We do not inflict anything, we propose. Every woman is free to accept, or not, the screening. Our duty is to inform so that everyone can make an informed choice. While its benefit is challenged by therapeutic progress, according to global studies, screening can prevent between 15 and 20% of deaths. That's why reading on the networks that there would be fake cancers I am amazed. This term, catastrophic, is harmful.

What's the risk ?

That misinformation leaves women, often the most at risk and the most precarious, out of the health care system. That cancers are treated later. But with this disease, we have no time to lose.

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<p><b>If mammography is so effective, why not organize screening before age 50?</b></p>
<p>Studies have not shown, today, a usefulness to detect as early as 40 years, for example. Before the age of 50, most of the 11,000 bad cancers affect so-called "surrogate" women. Those who have genetic or familial predispositions and enter a particular surveillance process. In addition, after 50 years, the composition of women's bads changes and the required radiation doses are lower.</p>
<p><b>The Ministry of Health, however, wants to implement a monitoring of 25 years. What is it?</b></p>
<p>This is a prevention consultation to badess risk factors, such as alcohol. Of the 59,000 bad cancers, 8,000 are attributable to it. We do not say it to be hygienists but to give benchmarks.</p>
<p><b>Another organized screening has just been set up for girls, that of cervical cancer. Should we expand the vaccination against papillomavirus to boys?</b></p>
<p>At INCa, we think we need to work on the vaccination of boys. To suppress a contagion, the vaccination coverage must be more than 50%. How to do if only one bad out of two is concerned? In small groups, I even used to say that restricting vaccination to girls is a badist measure.</p>
<h2 clbad=BREAST CANCER SCREENING: WHO IS CONCERNED

In France, there are organized screenings for three cancers: the cervix (since May 2008), the colorectal (since 2009) and the bad, since 2004. The latter concerns all women between 50 and 74, without symptom, nor any particular risk factor except … their age.

It is during this period that they are most exposed to the disease. A mammogram and a clinical examination done every two years make it possible to detect early a cancerous lesion to take it more quickly.

But screening has its limits: the risk of overdiagnosis or overtreatment, hence the criticisms that take root in France. Of the 28 Member States of the European Union, 25 have an organized bad cancer screening program.

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