Breast cancer: women who are in the morning would have less risk



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A new scientific study suggests that early-risers are less likely to develop bad cancer than others. We detail its main results.

Breast cancer: women who are in the morning would have less risk

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This is probably a study that will delight young parents who get up early every morning! According to a very serious study presented at a conference of the British Institute against Cancer (NCRI) in Glasgow, women who are in the morning would haven bad cancer risk reduced by 40% compared to evening women, who get up late.

Led by researchers from the University of Bristol, the study suggests that our internal clock, or circadian rhythm, may play a role in our likelihood of having bad cancer. Note that this circadian rhythm, which follows a cycle of about 24 hours, is specific to everyone and varies throughout life: for example, children are more likely to get up early than teenagers, and so on.

Here, the research team used a method called "Mendelian Randomization" to carry out this work: it involves identifying and using genetic variants related to potential risk factors, here the circadian rhythm, to determine whether or not there is a correlation between the latter and a disease, here bad cancer. This method is considered more reliable than other observation methods.

The study was based on data from 180,215 women enrolled in the British Biobank project and 228,951 women who participated in a global-genome bad cancer badociation study conducted by the international consortium BCAC (Breast Cancer Association Consortium). In all, 314 circadian rhythm variants were badyzed.

"Early bird" women better off than "night owls" for bad cancer

Verdict: The risk of bad cancer was 40% lower in patients with "early bird" genetic variants than in more evening females in BCAC data. Every additional hour of sleep beyond the recommended 8 hours has also been badociated with a 20% increase in the risk of bad cancer.

The data showed that over a period of eight years, approximately two women "late night" out of 100 will be diagnosed with bad cancer, against one woman "early bird" out of 100.

"We would like to continue the work to study the mechanisms underlying these results, since the estimates obtained are based on questions related to morning or evening preferences, and not to the question of whether people get up sooner or later late in the day. In other words, it may be that changing your habits does not change your risk of bad cancer, it can be more complex than that. ", nuanced Rebecca Richmond, lead author of the study.

"However, the results of our study on the protective effect of morning preference on the risk of bad cancer are in line with previous research highlighting the role played by night work and 'night light' exposure as risk factors for bad cancer", Concluded the researcher.

Source: University of Bristol

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