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In the five years preceding the onset of the first recognized clinical signs of multiple sclerosis, sufferers are much more likely to have certain conditions than others. A new study from the University of British Columbia (UBC, Canada) has just established the list and levels of badociation.
Patients with multiple sclerosis are up to four times more likely to suffer from chronic pain or sleep disorders before the disease starts. They are also 50% more likely to see a psychiatrist for depression, anxiety, mood disorder and bipolar disorder. Fibromyalgia, a condition characterized by generalized musculoskeletal pain, is three times more common in people who will be diagnosed with multiple sclerosis. Ditto for irritable bowel syndrome, almost twice as common in this population, and migraines
Antidepressants and antibiotics
The pre-pathological period was also badociated with greater drug use for musculoskeletal disorders, disorders of the nervous system and disorders of the genitourinary tract (bad and urinary tract), as well as antidepressants and antibiotics.
To obtain these results, researchers, led by Helen Tremlett, professor of neurology, examined the medical records of 14,000 people with multiple sclerosis, diagnosed between 1984 and 2014. They then compared them to the medical records of 67,000 healthy people.
"The existence of warning signs is well established for Alzheimer's disease and Parkinson's disease, but there have been few studies on multiple sclerosis," says Helen Tremlett . The essay, published in the Multiple Sclerosis Journal is the largest ever made in this area. "We now need to deepen our research: we want to see if there are discernible trends related to bad, age or type of MS developed," she continues.
Start treatment as soon as possible [19659004] This study could already allow physicians to diagnose and start treating multiple sclerosis earlier, which would be in line with the recommendations recently issued by American Academy of Neurology ]. According to the court, the best therapeutic strategy for slowing the progression of multiple sclerosis would be to start treatment as soon as possible, even before the disease develops.
Multiple sclerosis is an autoimmune disease of the central nervous system. It is due to a disruption of the immune system, which attacks the brain and nerve fibers by destroying myelin sheaths to protect neurons. Gradually, patients lose the use of their limbs, have problems with vision, motor skills and sensitivity. It is a multifactorial disease, which does not trigger around a single cause, but is the result of a "combination of circumstances", as explained in May by Professor Jerome de Sèze, neurologist at CHRU of Strasbourg and a specialist in multiple sclerosis
Multiple sclerosis is far from being a rare disease. Second neurodegenerative disease after Alzheimer's disease, it is the first cause of disability in young adults after road accidents. It affects around 100,000 people in France. 3,000 to 5,000 new cases are diagnosed each year.
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