Mechanism explains how degenerates fatty liver disease



[ad_1]

Mb (0) – sm Mt (0.8em) – sm "type =" text "content =" "NASH" (acronym for steatohepatitis nonalcoholic in English): this is the name of this liver disease, which in the United States has become the leading cause of liver transplantation in women and the second in men after alcoholic cirrhosis. this pathology mainly affects people with obesity or type 2 diabetes. It begins with what is known as fatty liver disease or soda. " A liver overloaded with fats is not pathological in itself and can be corrected with a little physical exercise and weight loss, but fibrosis marks the beginning of the inflammation typical of NASH "says Philippe Froguel of the University of Lille. has just unearthed an important player in the evolution of this disease, the growth factor PDGF A. " This protein, if it is produced in excess by the liver, becomes toxic and causes its fibrosis, a step before that of cirrhosis which can be fatal "adds Philippe Froguel. The researchers found that PDGF A could block insulin's ability to regulate liver function but also stimulate its own production, which […] "data-reactid =" 22 ">" NASH "(acronym for steatohepatitis nonalcoholic in English): this is the name of this liver disease, which in the United States has become the leading cause of liver transplantation in women and the second in men after alcoholic cirrhosis. this pathology mainly affects people with obesity or type 2 diabetes. It begins with what is known as fatty liver disease or soda. " A liver overloaded with fats is not pathological in itself and can be corrected with a little physical exercise and weight loss, but fibrosis marks the beginning of the inflammation typical of NASH "says Philippe Froguel of the University of Lille. just put in For an important player in the evolution of this disease, the growth factor PDGF A. " This protein, if it is produced in excess by the liver, becomes toxic and causes its fibrosis, a step before that of cirrhosis. can be deadly "adds Philippe Froguel. The researchers found that PDGF A could block insulin's ability to regulate liver function but also stimulate its own production, which is […]

Read more on sciencesetavenir.fr

Read also

[ad_2]
Source link