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A patient who had a double lung transplant developed lung cancer.
A patient from the University Hospital of Montpellier developed lung cancer after receiving a transplant of these two organs. Her donor had smoked the equivalent of a pack of cigarettes for 30 years.
At 39, a patient from Montpellier University Hospital thought she had left the disease behind. Having suffered from cystic fibrosis, she had benefited from a double lung transplant following "a sudden decrease in her breathing capacity," says Le Monde, which echoes the review Lung Cancer. But two years later, she pbades a lung radio that reveals "suspicious homes". The biopsy then confirms the presence of a cancerous tumor.
Immunosuppressive therapy involved?
The patient received her graft from a 57-year-old woman who had smoked the equivalent of 20 cigarettes a day for 30 years. However, the examinations performed on his lungs before the transplant had revealed no anomaly. For the doctors who followed the patient, the aggressiveness of the tumor could be due to the immunosuppressive treatment that she followed and which was prescribed to her at the time of the organ transplantation.
The case of this Montpellier patient is rare but not isolated. In his article in Le Monde, journalist and physician Marc Gozlan discusses cases of "liver cancer after liver transplantation and pulmonary cancer after lung transplantation". Recently, a study of the American Journal of Transplantation revealed that four patients who received organs from the same donor all had the same cancer. Three of them died.
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