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The gynecologist who helped to break the scandal of Distilbène in 1983 died Sunday in Paris at the age of 81.
The gynecologist who had helped to break the scandal of Distilbène in 1983, Anne Cabau , died Sunday in Paris at the age of 81 years, announced Monday the French Network, badociation of victims of this drug. "She was a whistleblower at a time when this term did not exist. Without his work, the case of Distilbène would never have burst, "said AFP Nathalie Lafaye, secretary of the badociation. This drug manufactured by UCB Pharma has been contraindicated to pregnant women since 1971 in the United States and in France in 1977.
Distilbene is the trade name of a synthetic hormone (diethylstilboestrol, or DES) prescribed in France between 1950 and 1977 to nearly 200,000 pregnant women to prevent miscarriages. These future mothers took this molecule without knowing that it would cause serious health problems to their children: bad cancers (cervix and bad) and bad, infertility and pregnancy complications for girls, risk of abnormalities bads for boys. As for the children of the "girls DES" (third generation), a study published in 2014 showed that they had a higher risk of having an obstruction of the esophagus at birth or bad malformations for boys. On the other hand, there was no increase in the risk of bad abnormalities in 3rd generation girls.
»READ ALSO -" Girls of Distilbène ": the risk of bad cancer doubled [19659005] 160,000 children exposed
In the early 1980s, when she was following young women for infertility, Dr. Anne Cabau, a young gynecologist, discovered that some had abnormalities of the uterus. While returning from the United States where she had completed her training, she made the link between these cases and American studies on girls Distilbene. She then decided to investigate the children of women who took this molecule and, between 1981 and 1982, she collected data on cases of malformations. His works are repeated in February 1983 in Le Monde under the title "The children of Distilbène: a monumental medical error."
"It has the effect of a bomb," says Nathalie Lafaye . "If scandals such as that of the Mediator (again revealed by a doctor, Irene Frachon, Ed) and Depakine then shook the country so much, it was because there had previously been the history of Distilbène.
A study published in 1983 estimated that about 160,000 children were exposed to Distilbene in utero . It was between 1964 and 1972 that the drug was the most prescribed. Numerous claims have been or are to be reviewed by the courts, some of which have already been compensated since the early 2000s.
In a landmark decision in 2011, the Court of First Instance Versailles appeal even acknowledged a connection between the taking of Distilbène and a third-generation disability, by awarding damages to the grandson of a woman treated with this drug.
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