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The effect of genetic relationships is stronger in women than in men.
REPUBLIKA.CO.ID, JAKARTA – Being overweight can cause depression, the researchers said. Overweight can affect the psychological state of a person, according to reported information. The Guardian which was launched Wednesday (11/14).
Previous research has shown that obese people tend to suffer from depression. But it is not yet clear whether depression encourages body weight changes or vice versa.
Today, in larger similar studies, experts say that having a high genetic variant badociated with BMI causes depression and that the effect is stronger in the women than men. In addition, they say research shows that it affects their body image.
"Overweight people in the community feel more depressed, which is at least a part of BMI's reciprocal impact on depression," said co-authors of the study. from the faculty of medicine of Exeter University of Professor Tim Frayling.
In an article published in the International Journal of Epidemiology, British and Australian researchers explained how they used data from the British Biobank, a study of 500,000 participants aged 37 to 73 years and recruited between 2006 and 2010.
The researchers examined 72 genetic variants badociated with high BMI, also badociated with various high-risk diseases such as diabetes and heart disease. They also examined 14 genetic variants linked to high percentages of body fat, but were badociated with a lower risk of these health problems.
The first group may be badociated with depression by biological or psychological mechanisms. While the second group is supposed to have only a psychological impact.
Overall, the team found that people with high BMI were likely to suffer from depression. Centered on 73 genetic variants and taking into account factors such as age and bad, they found that every 4.7 points increase in BMI, the possibility of depression increased by 18% in the Together 23% were women.
When the research team collected data from various sources, she discovered 14 genetic variants that increase adipose tissue but are not badociated with metabolic health problems, including an increase in the number of sufferers of depression.
"This shows that the psychological component is as strong as any physiological component, if (the last) is there," said Frayling, who shows a poor body image acting as a mechanism.
Naveed Sattar, professor of metabolic medicine at the University of Glasgow, is congratulated for the research. "These new discoveries are perhaps the strongest to date to show that overweight can actually contribute to depression.Of course, many other factors can be at the root of depression, but despite this, the Weight loss could help improve the mental health of some people.Knowing somebody slim in general will help reduce the risk of depression, "he said.
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