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Scientists have identified a liquid drainage system in the brain that sheds light on the underlying mechanisms of brain aging and Alzheimer's disease
The study demonstrated that lymphatic vessels Meningeal in the brain play a vital role in maintaining healthy homeostasis in the aging brain and could be a new target for treatment.
These vessels drain fluid from the central nervous system into the cervical lymph nodes and the dysfunction of this drainage worsens the cognitive decline as well as the pathology of Alzheimer's disease
. good health were treated with a molecule The size of the meningeal lymph vessels and the flow of fluids within these vessels improved the performance of learning and memory tasks.
"As you get older, the fluid movement of your brain slows down, sometimes up to half what it was. when you were younger, "said Jennifer Munson, an badistant professor at the Virginia Polytechnic Institute and the State University (Virginia Tech), in the United States.
"We have discovered that the proteins responsible for Alzheimer's disease are actually drained by these lymphatics into the brain with other cellular debris, so any decrease in the flow will affect this accumulation of proteins" she added. ] For the study, published in the journal Nature, the team has developed a hydrogel that can swell these lymphatic vessels.
As a result of the treatment, fluid flow in the brain increased, and this appeared to have a positive effect on cognitive abilities.
Munson noted that older mice with normal cognitive abilities, impaired by age experienced the greatest gains in memory and learning of treatment
"Our results showed that One day this method could be used as a potential treatment to help mitigate the effects not only of Alzheimer's disease, but also of other age-related cognitive disorders, Munson said.
– IANS
rt / mag / sed
(This story was not edited by Business Standard staff and is generated automatically from a syndicated feed.)
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