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| Hypertensive drugs containing carcinogens containing valsartan should not be discontinued. This can be caused by heart disease due to increased blood pressure. Measuring blood pressure with a blood pressure monitor. [제공=경희대병원] |
– Problem with hypertension, do not break
– It is best to exchange drugs as soon as possible.
[Herald Business = Shin Sang-yoon] In some products of valsartan used as a drug for the treatment of hypertension, N-nitrosodimethylamine (NDMA) As a result, the sequelae do not disappear. NDMA is a substance clbadified by the World Health Organization (WHO) under the name "2A" (a potentially carcinogenic substance in humans) by IAMC. As a result, the Korea Food and Drug Administration (KFDA) has taken temporary measures to suspend sales and manufacturing of 115 products containing raw materials.
Domestic hypertensive patients are estimated at about 6.04 million last year. It is about 12% of the total population (about 51.77 million ㆍ at the end of last year). So many people have to worry about their medications. This is because of the concern that "it can become more dangerous if you take medication to get sick." Experts say, "Do not take the medication once, but take it to the medical facility and pharmacy where you go early, and change it to a new drug.
– What is valsartan?
▶ (Kim Won Kyung, Professor, Department of Cardiovascular Medicine, Kyunghee University Hospital) Valsartan is an antihypertensive drug that inhibits angiotensin 2, a hormone that raises blood pressure by contracting Blood vessels. It has a cardioprotective effect and is also used for patients with hypertension, myocardial infarction and renal disease.
▶ (Kim Kyung-su, Professor of Family Medicine, Seoul St. Mary's Hospital, Catholic University of Korea) The problem is that valsartan is not a problem but a problem with it. Excipient which mixes it. Excipients are substances that help with the absorption and safety of medicines. The excipient is mixed with carcinogenic impurities.
– There is no side effect in valsartan itself
▶ (Kim Won) C is a drug that is used a lot. It has been proven safe by clinical use for nearly 20 years.
▶ (Kim Kyung-soo) Although there is no medication without side effects, the use of the right dose is one of the drugs used without problems for control hypertension.
– If you eat valsartan containing carcinogens, you may have cancer.
▶ (Kim Won) This was a preventative response to the announcement of the European Medicines Agency (EMA). Substances clbadified as "2A" by the IARC clbadification are considered to be cancer causing substances. The NDMA issue is now included in the group & # 39; 2A & # 39 ;. However, the probability of developing cancer varies according to individual health conditions. Carcinogens should be accumulated in the body to some extent, and cancer can occur. However, there is a need for future clinical studies to reduce the patient's anxiety. Until then, you should watch carefully.
▶ (Kim, Kyung-soo) I do not think you should deny the possibility of cancer
– What happens if you stop the drug that is dangerous?
▶ (Kim Won) There are also patients who can. You should consult your doctor immediately and replace the medicine.
▶ (Kim, Kyung-soo) Blood pressure rises and gives a lot to the heart, which can cause various heart diseases. It is best to take the medicine until you change the medicine.
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