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[베리타스알파=나동욱 기자] Gyeongsang National University, a team of Professor Kim Myung-ok of the Department of Biosciences and Biotechnology of the College of Natural Sciences, collaborated with Dr. Kim Sang-tae of Bundang Seoul National University Hospital to develop a revolutionary technology for the diagnosis of dementia. Dementia Early Diagnosis Biomarker & # 39; technology was also developed on the 2nd.
Professor Kim Myung-ok, professor at the BNIT R & D Center at Gyeongsang University, said: "In order to market an early diagnosis kit of dementia, the previous agreement was signed.
The government actively engaged in dementia, including the establishment of a 10-year national R & D plan to overcome dementia, and participated in the 10-student agreement ceremony. including Professor Kim Jong- And yet, he has not yet been able to identify the apparent cause of dementia.There is no biomarker diagnostic kit that can diagnose Appearance of dementia before amyloid plaque in the brain Dementia can be diagnosed with MRI or PET in severe cases, but in the end, it causes a lot of medical burden on the individuals, and the cost of medical wellness is also a big burden for the na
Professor Kim Myung- "This technology was developed not only for people aged 65 and older but also for the elderly such as the elderly diagnosed before the onset of dementia, Innovative Source Technology. "This technique can easily diagnose dementia from asymptomatic inflammation to dementia.
It is a technique to diagnose as a very low behavioral disorder, a language disorder, five senses (tactile / auditory) / taste / smell / sight) With the presence of the paralytic protein, nogo-A, accompanied by subjective symptoms, due to abnormal changes in the oligo Aβ and tau dementia.However, since the nogo-A protein begins to show signs of nerve palsy, a small amount of miR-21 signaling badociated with this exosome in the blood is secreted.Therefore, it can detect blood, hair, tears, sweat and urine containing biomarkers derived from man, and non-invasively identify the signs of dementia, so that the diagnosis and prevention of dementia can be diagnosed Can be exercised.
The technology developed allows very small amounts of nogo-A, oAβ, tau and other candidate biomarkers to be detected in blood or sweat waste, and can detect inflammation, pathogenic factors, Exosomal-mediated specific miRNAs can be detected with color or fluorescence by the "molecular blowtorch technique" to detect the presence or absence of early discrimination of dementia. When applied to smart phones, devices and experimental equipment, it is an early dementia diagnostic kit that uses molecular diagnostics to early detect the progression of the disease. dementia and determine the presence or absence of disease.
Professor Kim said: "In particular, early diagnosis of dementia kits should be possible within three years after clinical progress is faster than treatment, and if the technology is marketed, the market value will exceed 1 trillion won a year. " He said.
Professor Kim is currently a member of the Research and Development Committee for Research and Development on National Dementia. He held the position of Director of Development of Dementia Control and Convergence Research Technology for six years, until February. Currently, the Neurobiology Laboratory is the leader of the Metabolism Regulated Degenerative Disease Control Project, which includes 25 experienced researchers, and received the Gyeongsangnam-do Science and Technology Grand Prize last September.
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