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| Professor Lim |
It is reported that Koreans have less food and less obesity than Westerners, but the size of the pancreas is so small that the insulin secretion capacity of the pancreas decreases and diabetes is more likely to occur.
It has been reported that Koreans who are different from the West and their body size, and whose diet is small, have been diagnosed with diabetes mellitus
Professor Lim and his colleagues compared pancreatic volume (volume) and the pancreatic fat content of Koreans and Westerners with the help of a peak computed tomography. To investigate the relationship between insulin secretion and pancreatic beta cell function, we investigated the relationship between pancreatic size and fat content and insulin secretion.
People First, the fasting blood glucose and HbA1c levels were not different between the two groups, and there was no significant difference between the groups in total cholesterol , triglycerides, HDL-cholesterol and LDL-cholesterol
In comparison, the size of the pancreas was 12.3% smaller in Koreans than in Westerners, and the amount of fat deposited in the pancreas was 22.8% larger than that of Westerners.
The insulin secretion capacity was 36.5% lower than that of the western population. This result suggests that the absolute size of the pancreas in Korea is low and that the ability of insulin secretion in the pancreas is diminished even though it is similar to that of Westerner.
Diabetes is mainly caused by insulin resistance and insulin, which is caused by two mechanisms of pancreatic beta cell function. Here, the function of beta cells in the pancreas is damaged because of the insulin secretion is not properly reported, the beta cells in the pancreas is contained in a group of cells called sodo.
In addition, when the amount of fat accumulated in the pancreas is high, the amount of inflammatory substance secreted by the adipocyte is increased cytokines, vasoactive substances, and so on. are known to reduce beta cells and cause pancreatic dysfunction.
As a result, Koreans have a smaller pancreas size than Westerners and the pancreas secreted by the pancreas is deteriorated, moreover, the pancreas is more vulnerable to pancreatic function, making it difficult to control blood glucose. .
Professor Im said: "In order to accurately and objectively measure the volume of the pancreas using advanced computerized tomography, compare the Korean and Western population, and accurately measure the function of the pancreas," Given the fact that 10% of Koreans aged 20 and over (about 4 million) suffer from diabetes, compared to Westerners, the number of new diabetic patients "
On the other hand, it was the first time in the world that Koreans and Westerners study, which compared the size of the intestine to the function of diabetes mellitus in the Asian population, was published in the international journal on diabetes, Obesity and Metabolism.
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