MK News – Cecum Surgery to Prevent Parkinson's Disease



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The removal of the caecum by appendectomy reduces the risk of Parkinson's disease by 19 to 25%, according to a study. This study supports the hypothesis that the protein responsible for Parkinson's disease occurs in the stomach and should inhibit the onset of Parkinson's disease or be applied to a new treatment.

An international team of researchers, including the Van Andel Institute in Sweden and Lund University in Sweden, badyzed the medical records of 1.16 million Swedes and found that 1% of people with Parkinson's disease had 65 years or older. The rate of Parkinson's disease was 20% lower than that of people with Parkinson's disease. The results of the study were published in the latest issue of the International Journal of Science Mediation.

The appendix hanging at the end of the large intestine is often inflamed and must be cut. Cecum surgery, which cuts the cecum, was a common and easy procedure. The appendix is ​​a useless organ and it was recognized that it was a truncated organ if it became inflamed. The hypothesis that the cecum, called a useless organ, can cause Parkinson's disease was raised more than a decade ago. In the brain of patients with Parkinson's disease, the protein called "alpha-synuclein" is in the form of a misfolded mbad. Although the function of the alpha-synuclein protein has not been fully elucidated, it has been reported that neuroblastomas disrupt brain neurons by clumping together, causing symptoms of Parkinson's disease. such as tremors and stiffness. However, it has been reported that people with Parkinson's disease have frequent gastrointestinal diseases such as constipation. In addition, patients with chronic duodenal ulcer who have excessive secretion of stomach acid have a "vagotomy" that cuts the gastric nerve, involved in the secretion of gastric acid, which presents a low risk of contracting Parkinson's disease. Research has also been published. "A neuroscientist by the name of Heikobrach has suggested that the seeds that cause Parkinson's disease 10 years ago should come out of the digestive tract and reach the brain," Science said.

The researchers badyzed the medical records of 1.16 million Swedes to confirm this hypothesis. After badyzing the 52-year data, the researchers found that the risk of contracting Parkinson's disease was reduced by 19% in people with an appendectomy. Especially in rural areas, the probability of getting Parkinson's disease by appendectomy is 25% lower. Parkinson's disease is more common among people living in rural areas, probably due to exposure to pesticides.

A study of 800 patients with Parkinson's disease showed that patients operated on 20 years before the diagnosis of Parkinson's disease had a delay of 3.6 years in the onset of Parkinson's disease. There was no evidence of slowing the progression of Parkinson's disease in patients who had had appendicitis immediately before or after having Parkinson's disease.

Researchers in the cecum study have found in healthy people a block of alpha-synuclein proteins that causes Parkinson's disease. "Everyone had the wrong piece of alpha-synuclein protein in the appendix," he said. "But it seems like it only causes Parkinson's disease when it reaches the brain." It is interesting to note that when the normal alpha-synuclein protein was placed in an appendix-like environment, it became a good form to form pieces.

The cecum was a factory producing abnormal alpha-synuclein proteins responsible for Parkinson's disease.

This study suggests a new treatment strategy that can slow the onset of Parkinson's disease or reduce the risk of developing it. However, researchers have not recommended deliberately removing the caecum to prevent the onset of Parkinson's disease. "The cecum is known to be a useless organ, but it does not need to be cut because it plays an important role in controlling the body's immune system," said Professor Vivian Lavrie van Andel, who led the study. I can think about it, "he said.

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