[ad_1]
October 28, 2018 20:42
An impulse is a tendency to see an action or an immediate reaction depending on the mood regardless of the surrounding situation. Attention Deficit Hyperactivity Disorder (ADHD), Anger Crime and Addiction are mental disorders that can not control impulsivity. In Korea, ADHD tripled in three years from 2010 to 2013. In the United States, it has tripled in the last 15 years. According to the Health Insurance Assessment and Evaluation Service, patients treated for anorexic disorders in the last three years are increasing steadily each year to 5,390 in 2015, 5920 in 2016 and 5986 in 2017. Four- Twenty percent of people who have committed an anger-related crime regularly have impulse control problems.
However, it is not yet known how these impulses are controlled. Scientists are interested in the neurotransmission process in order to find ways to control impulsivity. National researchers have for the first time discovered neural circuits regulating impulsive behavior.
Professor Baek Jae-hyun from the University of Korea and Ryuichi Nakajima, a researcher at the Korea Institute of Science and Technology (KIST), discovered that a selective activation of neurons expressing the Dopamine D2 receptors in the central nucleus of the brain tonsil (CeA) could significantly reduce impulsive behavior. Says in a statement.
The researchers used Optogenetics, a method that uses light to modulate the activity of specific cells, to badyze the signals regulating the pulses in the experimental rat brain. We found that D2 receptor type of dopamine in cerebral amyloid plays a key role in impulsive control. The amygdala is an almond-shaped part of the cerebral limbic system that plays a role in emotions and emotions. D2 receptors are one of five dopamine receptors that influence exercise, cognition, and motivation.
The researchers conducted an experiment (5-CSRTT) that measured the impulsivity and concentration used in the diagnosis of ADHD patients. It revealed that mice lacking the dopamine D2 receptor exhibited significantly higher impulsivity than normal mice. Using photogenic methods, the selective activation of neurons expressing the dopamine D2 receptor in the amygdala showed that impulsive behavior was nearly 70% lower.
Professor Baek said: "We are supposed to help define therapeutic goals for serious mental illnesses in modern society, such as substance abuse, personality disorders and anger management disorders, because of a lack of self-control ability. " The study was published in the 22nd issue of the International Journal of the National Academy of Sciences (PNAS).
October 28, 2018 20:42
Source link
