"Type 1 and 2 diabetes, insulin pump therapy to improve insulin secretion, resistance"

"Type 1 and 2 diabetes, insulin pump therapy to improve insulin secretion, resistance"

Choi, Emeritus Professor of Su-bong, Konkuk University School of Medicine, American Diabetes Association

Choi, Su – bong, professor emeritus at Konkuk University, reported on research on insulin pump therapy. last year, after the European Congress last year.
Emeritus Professor Noh Yeon Hee and Professor Hong Eun-sil at the 78th Annual Meeting of the American Diabetes Association in Orlando, Florida recently released a paper on the effects and safety of the insulin pump for diabetic patients. type 1 and 2 Announced.

The first article published by Choi is "Improvement of beta cell function and insulin sensitivity by insulin pump therapy in patients with type 2 diabetes." The team has studied patients with type 2 diabetes mellitus (64% of men, 59.9 ± 9.1 years, 12.0 ± 9.2 years, HbA1c, 8.9 ± 2.0% and BMI of 23.5 ± 2.5) were studied for 3 years, the average HbA1c of patients was significantly reduced from 8.9% to 6.5%. In the insulin-responsive group, mean serum C-peptide was significantly increased during insulin pump therapy.

In the insulin-resistant group, the mean serum C-peptide did not change, but the mean sensitivity to insulin (MI) was significantly increased.

Clinical studies have shown that insulin pump therapy in patients with type 2 diabetes improves insulin secretion and insulin resistance in pancreatic cells, responsible for diabetes, by maintaining a normal blood sugar for a long time.

The second article published is "Reducing hypoglycemia and improving glycemic control in patients with type 1 diabetes using an open system of artificial pancreas (open PSA)." We used an insulin pump, a continuous glucose meter (CGMS) and an open artificial pancreas algorithm for 20 patients with type 1 diabetes (10 men, 10 women, mean age 12 years).

The badysis of the distribution of blood glucose before and after the use of the open artificial pancreas system showed that glycated hemoglobin was significantly reduced from 6.8% to 6.3%. The percentage of time required to maintain normal blood glucose (80 to 180 mg / dL) increased significantly from 70.1% to 83.3%.

In addition, the hourly rate of hyperglycemia with a blood glucose level of 180 mg / dL or more decreased from 24.7% to 13.3%. The hourly percentage of hypoglycemia lower than 80 mg / dL was significantly reduced from 5.1% to 3.4%.

Professor Emeritus Professor Emeritus Professor Emeritus Professor Emeritus Professor Emeritus Professor Emeritus Professor Emeritus Professor Emeritus, "The open artificial pancreas system is now available as a free and publicly available algorithm for the treatment of diabetes worldwide."

Kwon Dae-Ik, medical journalist

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