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A sildenafil trial during pregnancy was urgently discontinued following the death of 11 newborns
Sildenfail is an erectile dysfunction drug commonly sold under the brand name Viagra. The trial used a generic version of the drug not manufactured by Pfizer.
It seems that sildenafil used in the trial, which promotes blood circulation, could have caused lethal damage to the lungs babies.
Photo: 123rf
Women participating in the Dutch study had received anti-impotence tablets to improve the growth of their unborn children because they had poorly developed placentas.
It seems that the drug, which promotes blood flow, may have caused lethal damage to the lungs of babies.
Experts say that a full investigation is necessary to understand what happened.
There is no suggestion that there has been any harm.
in the United Kingdom and Australia and New Zealand have found no evidence of potential harm from the intervention.
At this time, in 2010, the researchers said the treatment should only be used in clinical trials.
The restriction of fetal growth caused by an underdeveloped placenta is a serious disease currently without treatment. 19659002] This may mean that babies are born prematurely, with a very low birth weight and low chances of survival.
A drug that could improve weight or prolong the delivery time could have significant benefits for these very sick babies. The last Dutch study, which was to last until 2020, was conducted in 11 hospitals in the Netherlands, including the medical center of the University of Amsterdam.
A total of 93 women received sildenafil while the other 90 received a manikin.
Twenty babies developed pulmonary problems after birth – three in the placebo group and the rest in the treated group.
Eleven patients in the sildenafil group died of pulmonary complications
Professor Zarcko Alfirevic, of the University of Liverpool, who led part of the British research on sildenafil during pregnancy and who did not have the disease. found no benefit in terms of improved growth, said: "This discovery is unexpected in the Dutch study.
" It needs a thorough investigation because the complications have not been observed in the two other similar trials that have already been done in the United Kingdom and in Australia and New Zealand. "[19659002] -BBC
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