One Dose of Pfizer Vaccine May Protect COVID-19 Victims From Reinfection: Study



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People with COVID-19 may only need one dose of Pfizer’s vaccine to be “sufficiently protected” against the virus, according to a new study.

The research, published in the JAMA Network Open on Friday, compared the antibody levels of people who had previously been infected with those who had not, after one and two doses of double-dose Pfizer.

“We observed higher SARS-CoV-2 antibody levels in previously infected individuals after one dose of BNT162b2 (Pfizer) compared to infection-naïve individuals after two doses,” University researchers said. Chicago Rush, who conducted the study.

Scientists said they found that giving a second injection of Pfizer to previously infected people did not “significantly increase” their antibody levels.

“People with a documented previous COVID-19 infection may be sufficiently protected against re-infection after a single dose of mRNA vaccine, which could free the availability of millions of additional doses,” the study concluded.

Pharmacy technicians prepare doses of the Pfizer-BioNTech vaccine during a mass vaccination against COVID-19.
The study found that giving a second injection of Pfizer to previously infected people did not “significantly increase” their antibody levels.
Michael Ciaglo / Getty Images

There is a severe shortage of vaccines in parts of the world, including India, where just over 7 percent of its nearly 1.4 billion people are fully immunized.

The latest reported searches involved 29 Chicago residents who previously had COVID and 30 who did not. The average age of the participants was 42, and about 75 percent were female.

The United States Centers for Disease Control and Prevention recommends receiving two doses of the Pfizer vaccine 21 days apart.

People 12 and older can currently receive the Pfizer vaccine, according to the CDC.

Quantitative SARS-CoV-2 IgG levels at baseline (blue dots), 21 days after vaccine dose 1 (orange dots), and 28 days after vaccine dose 2 (brown dots) in infection-naïve individuals or already infected.  The horizontal black bars represent the mean quantitative IgG levels (AU / mL) in the groups indicated.  The black dots represent 4 people with a previous positive SARS-CoV-2 polymerase chain reaction but had no detectable SARS-CoV-2 IgG to begin with.  The horizontal blue line indicates the limit of detection assay limit.  Statistical analysis was performed using an unpaired two-tailed t test.  AU indicates an arbitrary unit.
People with COVID-19 may only need a single dose of Pfizer’s vaccine, according to a new study.
Mark Anderson et al.

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