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(Caracas, July 25, Europa Press) – Four new studies presented at the International Conference of the Alzheimer's Association (AAIC) 2018 in Chicago (USA) investigated how the Digestive system including intestinal and hepatic functions may be related to changes in brain and brain disorders such as Alzheimer's disease and other dementias.
The intestinal microbiome is the community of microorganisms the digestive tract, with a thousand different species of bacteria. Science has correlated some changes in these intestinal bacteria with a variety of inflammatory and autoimmune conditions. And studies have shown that dietary changes can change intestinal bacteria.
In a recent study we learned a lot about how diet, especially general eating habits may be related to brain health, cognitive decline and perhaps even dementia as we get older. We also observed inflammation and its markers, in the brain and other parts of the body, associated with Alzheimer's disease and other dementias.
Exactly how microbes interact with the brain and influence brain health, such as cause, trigger or risk factor / protection, is a relatively new area of research for Alzheimer's and Alzheimer's disease. other dementias. For example, scientists recently reported that certain species in the microbiome can promote protein accumulation in the brain.
This may be important because the accumulation of amyloid proteins and tau is characteristic of Alzheimer's disease. Recent reports of experiments on mice suggest that changing the bacterial profile in your digestive tract by changing your diet can reduce amyloid plaques, decrease inflammation and improve memory.
At the same time, a growing body of evidence suggests that the impaired metabolism of some lipids may be an important factor in the development of Alzheimer's disease because they constitute the mass of the brain mass.
"Even in its early days, research on the gut microbiome is very exciting, it can give us a new window on why diet and nutrition are so important to brain health," said María Carrillo, scientific director of Alzheimer's Association. This work can give us more information on how and why the "good fats" help keep the brain healthy and help guide healthy dietary choices for the brain.
"Also, it turns out that these intestinal bacteria are effective and accurate markers of the cause or progression of Alzheimer's disease, or both, might be helpful as a non-invasive screening tool, simple blood test. Then they could be used to help identify people at high risk for clinical trials or to track the impact of a therapy, "says Carrillo.
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