Two espressos a day, a healed boy, 11, who could barely walk because of shakes resembling Parkinson's disease



[ad_1]

Two espressos a day, a healed boy, 11, who could barely walk because of shakes resembling Parkinson's disease

  • An 11-year-old boy was diagnosed with ADCY5-related dyskinesia, a condition that causes abnormal involuntary movements
  • Researchers in Paris, France, have decided to prescribe caffeine to activate receptors for an enzyme that plays a role in muscle contraction
  • An espresso cup stopped the tremors for seven hours and two cups kept them at bay all day long
  • When his parents tried decaffeinated coffee, the boy had tremors up to 30 times a day

Two cups of espresso a day healed an 11-year-old boy who could barely walk because of tremors resembling Parkinson's disease.

In a new case report, published in the Annals of Internal Medicine, the young teacher was diagnosed with a disorder known as ADCY5-related dyskinesia, which caused him to shake and shake involuntarily.

Researchers at Hospitals in Paris, a French university hospital, decided to prescribe caffeine to relax his muscles and activate the receptors of an enzyme that plays a role in muscle contraction.

An espresso cup stopped her tremors for up to seven hours, while two cups helped prevent nerve contractions for almost a whole day.

Moreover, when the boy's parents gave him decaffeinated coffee, the jerky episodes came back in force – and up to 30 times a day.

An 11-year-old boy in Paris, France, was diagnosed with ADCY5-related dyskinesia, a condition that caused him shaking and involuntary shaking. The researchers therefore decided to try to treat it with an espresso. (Image of the file)

An 11-year-old boy in Paris, France, was diagnosed with ADCY5-related dyskinesia, a condition that caused him shaking and involuntary shaking. The researchers therefore decided to try to treat it with an espresso. (Image of the file)

Dyskinesia related to ADCY5 is a disorder that requires people with abnormal involuntary movements.

These movements include jerking, contractions, tremors, or convulsions in the face, neck, arms, and legs.

According to the National Institutes of Health, about 400 people worldwide have been diagnosed, but its prevalence is unknown.

It is caused by a mutation in the ADCY5 gene, which provides instructions for making an enzyme involved in muscle contraction.

This enzyme is activated by the adenosine receptors, the main target of caffeine.

The researchers hypothesized that caffeine would inhibit the enzyme and reduce the involuntary movements of patients.

In the case report, the authors write that the boy started making involuntary movements at three years, which could last from a few seconds to 10 minutes.

At the age of 11, he was experiencing nearly 30 episodes a day and was having difficulty performing activities such as walking, writing in class and cycling.

The doctors decided to prescribe coffee, gradually passing from one cup to almost three cups.

Although the treatment of ADCY5-related dyskinesia is not known, caffeine is known to relax muscles.

The boy started drinking an espresso cup, containing about 100 milligrams of caffeine, each morning.

A mug stopped the tremors for seven hours, 7 minutes while adding a second cup in the afternoon and half a cup in the evening, almost completely stopped them.

When his parents accidentally bought decaffeinated coffee, the contractions and tremors of the boy came back in force.

His mother and father realized the mistake four days later and immediately bought coffee containing caffeine, which resulted in the disappearance of his episodes of dyskinesia.

"We have interpreted these events as a casual, double-blind experience in real life," the authors wrote in their report.

"In light of this strong logic and our experience with our patients, we believe that caffeine could be an effective treatment for others with ADCY5-related dyskinesia and should be considered in all patients."

[ad_2]

Source link