[ad_1]
L & rsquo; Investigated a large amount of genetic data collected from the DNA test site 23andme and a British "biobank" to better understand what makes a man a day or night.
"This study is important because it confirms that morning or evening preference is determined, at least to some extent, by genetic factors," said Michael Weedon, a professor of medicine at the University of Toronto. Exeter, who directed the research.
The study is the largest of its kind – it badyzed the s data of nearly 700,000 people – and revealed that a much larger amount of genetic factors is related to when people sleep and wake up compared to the known past.
Researchers knew only about 24 sleep-related genes, but the new study published Wednesday in Nature Communications revealed that another 327 also play a role in this process.
The badysis also showed that people with a genetic tendency to sleep later are at higher risk for mental health problems, such as schizophrenia, although the authors warned that more work was needed. to understand the link.
The initial phase of the research included the badysis of self-described genes as "day people" or "night people".
As these terms may mean different things to different people, the researchers looked at a smaller group of participants using activity follow-ups.
Researchers looked at tracker information from more than 85,000 participants at the British Biobank to find objective data on their sleep patterns.
They found that the genes that they had identified could alter a person's natural wakefulness in less than 25 minutes, but there was no apparent link between them. genes and duration or quality of sleep of people
– "Person The study also examined why some genes influence sleep and waking of people, finding differences in how the brain reacts to light and in the operation of internal clocks.
To test long-standing theories about the links between sleep patterns and certain diseases, researchers also examined the correlation between the "morning" and "night" genes and various disorders.
They found that a genetic tendency to sleep and wake up earlier seems to be linked to a lower risk of depression and schizophrenia, as well as greater well-being.
However, Weedon admitted that it was not clear whether the call was directly related to being a "morning person" or whether it was caused by the fact that early birds have an easier life at work from 9am to 5pm. .
Researchers are considering whether "genetically nocturnal people have worse results if they are active in the morning compared to those whose genetics and activity are aligned," he said.
The study found no evidence of a causal link between genes that affect sleep duration and metabolic diseases, such as type 2 diabetes.
But future research will examine the issue in individuals whose natural sleep patterns are incompatible with their lifestyles.
"For example, genetically nocturnal people who have to wake up early because of work commitments are particularly exposed to obesity and diabetes?"
[ad_2]
Source link
