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Gustavo Menezes – Researcher UFMG – Photo William Araújo – Minas Faz Ciência
"All substances are toxic, there is nothing but a poison."
Sentence attributed to Paracelsus, Swiss physician and physicist of the sixteenth century
The study of the researcher Gustavo Menezes, Department of Morphology of the Institute of Biological Sciences (ICB), Federal University of Minas Gerais ( UFMG), on anti-inflammatories and reactions in the body, also participates in anti-drug measures. According to the scientist and his collaborators, the dosage and timing of use of symptomatic remedies, such as paracetamol and tylenol, if they are not correct, may delay tissue repair and result in another set complications.
Inflammatory Response
Menezes explains that the inflammatory response observed a few decades ago was a disease . What's an error? The inflammatory process is a body resource that, in the interest of restoration, promotes the fight against the strangeness of the body, generating symptoms such as pain, edema and fever.
In information provided to the UFMG press office, Menezes compares the inflammatory response c of "a city hit by a missile: to rebuild, it is necessary to demolish the damaged buildings and clean up the Neutrophils, defense cells that quickly reach inflamed tissue, must digest dead tissue so that the organ can replenish itself, so blocking their action completely and for long periods prevents tissue from repairing itself. correctly. "
Faced with this discomfort (symptoms) caused by several factors, such as pathogens, people minimize the problem with anti-inflammatory drugs. According to the researcher, this is not necessarily a problem, provided they are prescribed at the exact moment by health professionals.
Complications occur when patients do not seek medical badistance . what dosage and for how long. According to the study, in the case of anti-inflammatory drugs, over-medication causes increased resistance to the active ingredients of the drug ("the body learns to destroy drugs more quickly") and delays the healing of tissues affected by
"The processes etched by evolution are a gift for human fixation on the earth," says the researcher.
According to Menezes, among the three possible times for the use of these drugs (before the onset of symptoms, during and after symptoms). symptoms have ended), the worst response occurred when anti-inflammatory drugs were prolonged for no reason. However, when there was a medical intervention shortly after the onset of symptoms, the responses were better.
The ease of buying anti-inflammatory drugs creates an unprofitable self-medication culture. "People feel a slight headache and start taking the medicine.After the end of the symptoms, they continue to take precautions.
The scientific document was recently published in Revista Cells under the name Role paradoxical matrix metalloproteinases in liver lesions and regeneration after sterile acute hepatic failure To access, click here
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