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A group of scientists has managed to convert bad cancer cells into fat cells, which do not divide and spread throughout the body, thus avoiding the dreaded metastasis.
Cancer control: an innovative technique for converting diseased cells into simple fat
One of the features that make cancer very deadly is that it can spread throughout the body, affecting not only the organ in which it appears, but also all the rest of the body. organization.
In medical terms, we speak of metastasis. But now, a new treatment based on bad cancer cells – and that until now has been tested only in mice – has given excellent results to prevent this phenomenon.
The findings come from a survey conducted by scientists from the Department of Biomedicine at the University of Basel. , Switzerland, published in the journal Cancer Cell. Cell Growth
Generally, cancer cells can modify their molecular properties to adopt the characteristics of other cell types and thus distinct from the original group. Once released, they can migrate to other parts of the body through the bloodstream
. This process, called epithelial-mesenchymal transition, is essential for embryonic development. And with regard to cancer cells, it is the most powerful weapon to spread the disease.
In their studies, the group of scientists from the Swiss university could use this process to act against the tumor cell itself, preventing it from entering
Indeed, when cells change their properties to initiate epithelial-mesenchymal transition, they also become more mutable
Scientists gave rodents used in research a combination of two drugs: trametinib, type 2 diabetes called rosiglitazone, and an inhibitor of the growth and spread of cancer cells.
According to research, the treatment showed that cancer cells were converted to fat instead of continuing cell division
The fat cells obtained are the same as ordinary fat cells, which can not be transferred to other cells. other tissues.
Those participating in the study hope that in the future, a therapy can be used in conjunction with chemotherapeutic treatments and thus prevent the growth of the tumor and its spread to other organs or tissues [19659017BBCisnotresponsibleforthecontentofexternalinternetsites
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