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The National Health Surveillance Agency (Anvisa) warned of the increased risk of skin cancer badociated with the prolonged use of one of the most widely used drugs for the control of hypertension, hydrochlorothiazide . The badociation of the drug with the onset of skin cancer is the result of recent studies and therefore of a novelty in the medical community, as explained the use of the drug. [196459004] Miguel Morita Fernandes da Silva, Cardiologist of the Quanta Diagnosis and Therapy Research Department. And although it is a well-designed study with Danish national data, this does not mean that there is a direct link between substance and disease:
"The cancer risk resulting from the use of drugs is very difficult to exploit because it's usually the result of long-term exposures and it's also something more rare.This study showed an badociation, but that does not mean that the use of hydrochlorothiazide causes skin cancer.There is no way to exclude other factors that influence this outcome, such as the habit of these people to wear sunscreen, "says Silva, who is also a professor of medicine at PUCPR
Another detail, as the cardiologist reminds us, is that the Danish study took into account the data of patients of exclusively white ethnicity. " this badociation between the hy drochlorothiazide and skin cancer does not apply to blacks. And they suffer more from high blood pressure, "says Silva.
>> Anvisa Prohibits the Use of Medicines Against Hypertension and Heart Attacks
Should I Change a Remedy?
Despite the alert, the position of Anvisa and the community of Cardiologists and dermatologists are clear: Do not stop taking your medicine even if it is not safe. it contains hydrochlorothiazide. Indeed, cardiovascular risk, which the drug prevents, is more important for the health of the hypertensive patient than the risk of skin cancer – at least in the short term
"Sudden arrest increases the risk of hypertensive crisis. There are some means of control, such as increasing the dose of other drugs.The evidence is insufficient to suggest that hydrochlorothiazide should be removed.The main warning is that these people are protecting themselves more from the sun, "reinforces the cardiologist Miguel Morita Fernandes da Silva
If in doubt, talk to the cardiologist. Hydrochlorothiazide is a diuretic drug of the clbad Thiazides, usually indicated for people more prone to water retention or obesity. It has been designated as the main drug against hypertension, but currently, faced with an increased supply of other substances, it can be replaced without harming the health of the patient
showed an badociation between people who took a drug for high blood pressure and the development of skin cancer without melanoma (Photo: Bigstock) [19659012]> Why avoid ready-to-eat spices can be better for health?
skin without melanoma
Some drugs usually generate photoallergic reactions, according to Giseli's Mattos Diosti Stein, a dermatologist, and hydrochlorothiazide is one of them. As a light-sensitive drug, ultraviolet radiation increases the risk of skin lesions
. The relationship with the increased risk of developing a specific skin cancer is however new. The risk, it seems, is related to squamous cell carcinoma skin cancer and basal cell carcinoma, although a little less in the latter.
"Skin cancer is the most common cancer, and non-melanoma cancer accounts for 90% of all skin cancer cases, unlike melanoma, which is a cancer that can cause death. Melanomas, when diagnosed early, have a high cure rate, "says Giseli, a dermatologist in Neoderme, a member of the Brazilian Society of Dermatology and the group. Brazilian Melanoma
Among the most important signs of non-melanoma, he points out the reddish marbles that appear through the skin, like wounds that do not heal. It is also in the form of peel patches and is also red. In the case of melanoma, skin cancer is in the form of black and dark spots.
"Skin cancer usually has a progressive growth plan that is slow, but does not go away spontaneously.The treatment, in most cases, is surgical," says the dermatologist.
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