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The curative has a gel form and can be used as an anti-inflammatory wound, burns and ulcer wounds
Brazilian scientists have developed an anti-inflammatory dressing combining a pineapple protein – bromelain – cellulose produced by bacteria (bacterial nanocellulose). The study was published in the journal Nature & # 39; s Scientific Reports
The dressing has a gel form and can be used as an anti-inflammatory wound, burns and ulcer wounds. Indeed, bromelain has the property of breaking down molecules into proteins – to the point of being used as a meat tenderizer – by eliminating dead cells, cleaning the wound and accelerating healing
"Whoever has Serious injury is well aware of the difference that makes a good dressing.It must create a barrier against microorganisms, avoiding contaminations, and be able to provide antioxidant activity to decrease the inflammatory process of dead cells and pus ", explains researcher Angela Faustino Jozala, coordinator of the Laboratory of Industrial Microbiology and Fermentation of Uniso. one of the authors of the study
In order to achieve the result of the anti-inflammatory dressing, laboratory tests were carried out, submerging, for 24 hours, membranes of bacterial nanocellulose in bromelain solution. With this, a nine-fold increase in the antimicrobial activity of nanocellulose could be noted. In addition, a barrier has been created that has potentiated the activity of proteins and other important mechanisms for healing, such as the increase of antioxidants.
"Uninfected skin has the biggest problem of contamination, the patient is likely to be infected with either burns, wounds or ulcerative wounds Bromelain creates such an important barrier. done in our study was to potentiate, with bromelain, the healing action of this nanocellulose that we were already producing in our biomanufacturing platform. "
While bromelain has the ability to clean the necrotic tissue of the wound , forming a protective barrier, bacterial nanocellulose temporarily replaces the skin and is used as a dressing in the treatment of the lesion, relieving pain and protecting against infection.
"We were producing bacterial nanocellulose, but we wanted to extend the healing powers of the product." From a meeting with the Unicamp group, which has already extracted bromelain using the remains of the industry of the paste, we saw that the junction had a future. "
The study was conducted in a partnership of researchers from the University of Sorocaba (Uniso) and the State University of Campinas ( Unicamp), with the support of the Foundation for the Support of Research of the State of São Paulo (FAPESP)
Sources:
BBC-Brazilian Pineapple that facilitates healing
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