Can intensive blood pressure control reduce the risk of dementia? Alzheimer's disease and other dementias are one of the major health problems in the world: about 50 million people currently live with this disease.

. To do this, researchers conducted a randomized clinical trial at 102 sites in the United States and Puerto Rico with adults aged 50 or older with hypertension. but without diabetes or history of stroke. The main outcome was a composite of cardiovascular events and all-cause mortality. The study was interrupted early

Control of blood pressure and risk of dementia

The 9,361 participants (mean age of 67.9 years, 35.6% women) of the study were randomized into two interventions:

• Intensive blood pressure control: <120 mmHg (n = 4,678)
• Standard blood pressure test: <140 mmHg (n = 4,683)

Duration average intervention was 3.34 years. The main cognitive outcome was the likely occurrence of dementia; the secondary ones included mild cognitive impairment and a composite of mild cognitive impairment or probable dementia.

Dementia: Why is prevention more effective than treatment?

] During a median follow-up median of 5.11 years, a probable dementia occurred in 149 participants of the intensive care group against in the group Standard treatment (7.2 vs 8, Intensive control of blood pressure significantly reduced the risk of mild cognitive impairment [6][6][5][5] and [5]. (14.6 vs 18.3 cases per 1000 person-years; HR : 0.81, 95% CI 0.69 to 0.95) and the combined rate of mild cognitive impairment or probable dementia (20.2 vs In the study population, the prevalence of the disease was 0.9 to 0.97 (p <0.001). (<120 mmHg) did not result in a significant reduction in the risk of probable dementia, but revealed significant findings regarding the risk of mild cognitive impairment