Fecal transplantation: "Why did I decide to become a fecal donor?"

Claudia Campenella, 31, works as head of student support service at a university in the United Kingdom and is a stool donor in her free time

" Some friends think it's a little strange or disgusting, but it's all the same.It's very easy to donate and I just want to help medical research.I am happy to contribute. "

The material, filled with" good " bacteria, will be used in stool transplants, consisting of transferring the stool of a donor (bad, oral or nasal) into the intestine of another patient, as a form of treatment for intestinal diseases

Campenella knows that giving is extremely useful – that's why she does volunteering – but what does she qualify for?

Scientists believe that the excrement of some

Campenella says she decided to start donating because she had read that vegans could be particularly qualified candidates

There is no evidence He It is clear that feces from vegans are better than others, but researchers are studying what can make feces "superior".

Feces
Our intestines harbor millions of bacteria that live in a kind of community.

Although fecal transplantation is still a relatively new medical field, studies suggest that some donors offer better quality material for the procedure

"We see grafts reach remission rates that are perhaps twice as high as the average," says O & # 39; Sullivan.

"We hope that, if we can understand how this happens, we can improve the success of fecal transplantation and even test the procedure for new conditions badociated with the microbiome, such as Alzheimer's, multiple sclerosis and asthma."

Jon Landy is a Network Gastroenterologist

He accepts the idea of ​​a "super-performer" but says that it can be complicated to find one .

"We always make sure that donors are healthy individuals and have no disease, but we do not test the microbiome as a whole to see what it looks like."

"These are searches of this kind that we must do."

Fecal Bacteria
The research of O. Sullivan, published in the scientific journal Frontiers in Cellular and Infection Microbiology, indicate that the presentation of a wide variety of micro

According to him , the presence of a greater number of species in the donor's feces has proven to be one of the factors that most affect the outcome of fecal transplantation.

But studies suggest that the success of the procedure may also depend on the donor's compatibility with the patient.

And it may not be just a question of "

" Some cases of recurrent diarrhea infection have been cured with filtered stool transplants. All living bacteria are filtered but still contain DNA, viruses and other debris. "

viruses can affect the survival and metabolic function of bacteria and other grafted microbes," says O. Sullivan.

Julie McDonald, microbiome specialist at Imperial College London, England, is studying ways to increase the success rate fecal transplants.

Currently, most donations are used to treat Clostridium difficile infections, which can occur when the patient's "good" intestinal bacteria are removed by antibiotics.

McDonald's research suggests that fecal transplants play a very specific role, replacing something that has been lost as a result of the disease.

She found that patients with Clostridium difficile showed almost imperceptible rates of short-chain fatty acid valerate produced by microbial metabolism of the healthy gut.

Rates could only be restored with successful fecal transplantation.

learn exactly how grafts work and we even see if we do not transplant the stool itself. "

Instead of giving the patient a fecal injection, he would receive a stool-based treatment that could be considered less invasive.] In her opinion, this could help to get around the taboo problem related to stool donation. [19659005CampeNellawantspeopleto"overcomethepsychologicalbarrier"andconsiderbecomingadonor

"To give is very easy. It's easy to do. If you think about it, make sure that a nearby hospital offers the service and contact him. "

" I collect my new sample at home in a container provided by the hospital. And I leave the hospital on my way to work. It's just a small effort, "she adds.

She is now planning to become a blood donor too.

" I have not donated yet, but this is not enough. " Is something that I could do. "f, b, e, v, n, t, s)
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