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This is the "fifth concept vaccine" against HIV tested in 35 years
July 10, 2018, 12:46 pm
. (19459015) Experimental HIV which caused an immune response in humans and protected the monkeys against infection
The development of this potential vaccine, safe for the man, is advanced enough that it can be tested in 2,600 women in the Africa Southern
"These results represent a significant step" for the creation of a vaccine, the study's lead author, virologist Dan Barouch, said in a statement in the medical journal The Lancet.
However, he warned that there is no guarantee that future tests will be positive. "
Two-thirds of the rhesus monkeys that have been treated have been protected by the vaccine in laboratory tests.
The most important test results are expected for 2021 or 2022. [19659008] C & # 39, is the fifth "vaccine concept" against HIV tested in 35 years, according to Barouch.
Another, called RV144, has shown that it protects humans from HIV to some extent. In 2009, a study indicated that it had reduced by 31.2% the risk of infection by 16,000 volunteers in Thailand
. The study published on Saturday looked at 393 elderly healthy and seronegative adults aged 18 to 50. Eastern Africa, Southern Africa, Thailand and the United States Some of them received a placebo
The tests showed the safety of the combined vaccine, which included different types of HIV virus, with only five participants having adverse effects such as diarrhea o
These same vaccines protected two-thirds of the 72 monkeys
"We need so many vaccines," said Francois Venter of the University of the Witwatersrand (South Africa). But "we already know this: promising experimental vaccines that do not materialize."
"This is probably not the definitive vaccine, but it can be a phenomenal breakthrough," said Jean-Daniel Lelièvre of the Vaccine Research Institute. "At best," this research will produce a manageable vaccine in "nearly 10 years."
About 37 million people are living with HIV or AIDS, according to the World Health Organization (WHO) 8 million people contract it each year. The disease has killed about 35 million of the 80 million that it has infected since its first diagnosis in the 1980s.
Despite advances in medicine in the prevention and treatment of diseases, researchers emphasize the measures which must be taken to be infected: protection during bad, use of new syringes, sterilization of medical equipment, etc.
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