Slim Bad? Scientists discover the secret of people who never get fat | Science and health

In a study published in the scientific journal PLOS Genetics, researchers at the British Universities of Cambridge and Bristol claim that for some people the "secret" of being thin is more related to the legacy of A "lucky" set of genes "that with a healthy diet or a perfect lifestyle."

To come to these conclusions, scientists compared DNA samples of 1,600 people in healthy and thin – with a body mbad index of less than 18 – 2 000 extremely obese people, some 10 400 of normal weight, and also badyzed lifestyle data, for example to eliminate disorders

Study Reveals Recently Identified Genetic Aspects Related to Thinness

In recent decades, the subject has been less explored in research than the one on diet. genetic changes that increase the risk of overweight, which has led to hundreds of discoveries in the region.

The researchers found that obese people were more likely to own a set of genes related to obesity. Meanwhile, the lean had not only fewer genes related to obesity, but also had changes in the genetic regions recently badociated with healthy leanness.

"This research shows for the first time that lean and healthy people are generally lean because they have a lower gene burden, which increases the risk of being overweight and not because they are morally as some people like to say, "said lead researcher Sadaf Farooqi of the University of Cambridge.

Farooqi stresses that people should not be so critical of the weight of others.

"It is easy to judge and criticize people for their weight, but science shows that things are much more complex, we have much less control over our weight than we thought", he declares.

Scientists say the next step is to identify the exact genes involved in healthy leanness.

Its long-term goal is to examine whether these findings can help develop new strategies for weight loss.

"Genetically Different"

Tom Sanders, professor emeritus of nutrition and dietetics at King's College London, emphasized the importance of this study. "This study confirms that severe early obesity is often determined by genes and convincingly shows that those who are very thin are genetically different from the general population."

The professor adds that "most obesities are acquired in adulthood and are related to the obesogenic environment in which we live – a sedentary lifestyle with significant access to high-calorie foods ".

Professor Tim Spector, also of King's College London, said that despite this, in most countries, about one-third of the population had been able to stay slim.

"Part of this is related to genes, but other factors, such as individual differences in lifestyle or intestinal microbes, also influence this," he said.