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Scientists say they have discovered why some people never gain weight, while others easily gain weight.
To reach these conclusions, scientists compared DNA samples from 1,600 healthy and lean people – with a body mbad index below 18 – to those of 2,000 extremely obese people and 10,400 people of weight. normal. They also badyzed lifestyle data, for example to eliminate eating disorders.
The study reveals recently discovered genetic aspects related to thinness.
In recent decades, the subject has been less explored in research than that on genetic changes that increase a person's risk of overweight – which has led to hundreds of discoveries in the region.
What does the study show?
The researchers found that obese people were more likely to own a set of genes related to obesity. Meanwhile, the lean had not only fewer genes related to obesity, but also had changes in the genetic regions recently badociated with healthy leanness.
"This research shows for the first time that lean and healthy people are generally lean because their gene burden is lower, which increases the risk of being overweight and not because they are morally superior. , as some people like to say "Sadaf Farooqi, principal investigator of the Cambridge University study.
Whatever your constitution or genetic makeup, old recommendation to exercise and follow a healthy diet is still valid.
Photo: Getty Images / BBC News Brazil
The Weight of Others
Farooqi stresses that people should not be so critical of the weight of others.
"It is easy to judge and criticize people for their weight, but science shows that things are much more complex, we have much less control over our weight than we thought", he declares.
Scientists say the next step is to identify the exact genes involved in healthy leanness.
Its long-term goal is to examine whether these findings can help develop new strategies for weight loss.
"Genetically Different"
Tom Sanders, emeritus professor of nutrition and dietetics at King's College London, stressed the importance of this study. "This study confirms that severe early obesity is often determined by genes and convincingly shows that those who are very thin are genetically different from the general population."
The professor adds that "most obesities are acquired in adulthood and are related to the obesogenic environment in which we live – a sedentary lifestyle with much access to high calorie foods ".
Professor Tim Spector, also of King's College London, said that despite this, in most countries, about a third of the population had managed to stay lean.
"Part of this is related to genes, but other factors, such as individual differences in lifestyle or intestinal microbes, also influence this," he said.
Health experts say that, regardless of their genetic makeup, the former recommendation to exercise and adopt a healthy diet is still valid.
BBC News Brazil – All rights reserved. Reproduction is prohibited without the written permission of BBC News Brazil.
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