Start in 2019 tests to treat Alzheimer's disease in humans



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Sydney, Australia. Researchers at the University of Queensland Australia are about to test in humans a treatment for Alzheimer's disease using microscopic gas bubbles. Experimental treatments should begin at the end of 2019.

According to the team, in contact with ultrasonic energy, these gas bubbles are able to break the barriers preventing the removal of amyloid plaques (interfering with the synapse process of neurons). Earlier this year, the project had already been successful in reversing dementia symptoms and lowering plaque in older mice.

"All brains change with age, becoming more fragile," he said. in February, the researcher Gerhard Leinenga. "The rats we treated in this study would be equivalent to humans in their 80s and 90s," added Leinenga.

Pankaj Sah, a professor in the field of brain study at the university, confirmed that tests had shown the temporary opening of a blood-brain barrier, which facilitated the removal of toxic plates. All symptoms were successfully reversed and the memory functions were restored, at least in animals.

The blood-brain barrier is composed of flattened cells that surround all the blood vessels of the central nervous system. It is used to protect the nervous tissue from toxins that circulate in the blood, in addition to allowing (or not) the entry of respiratory gases, sugars and hormones. There is currently no approved treatment for Alzheimer's disease, but only medications to control side effects.

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