Stool graft: "Why do I decide to become a stool donor?"



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31-year-old Claudia Campenella works as head of student support at a university in the United Kingdom and, in her spare time, gives stool.

"Some friends find this a little strange or disgusting."

The material, filled with "good" bacteria, will be used in fecal transplants – which involve transferring the (19659002) Campenella knows that the donation is extremely helpful – that's why she's volunteering – and that's why she's willing to donate to another patient's gut as a treatment for bowel-related diseases.

Scientists believe that some people's stools may contain an ideal mix of healthy bacteria to treat intestinal diseases, making them "gifted".

Campenella says he decided to start donating p

There is no solid evidence that fecal matter from vegan people is better than others, but researchers are studying what can make feces "superior". 19659002] Our intestine is home to millions of bacteria that live in a kind of community.

Although fecal transplantation is still a relatively new field in medicine, studies suggest that some donors offer better quality material for the procedure

Justin O. Sullivan, a specialist in molecular biology at the University of Ottawa. University of Auckland in New Zealand, is studying the concept of "super-donors" of feces.

"We find that grafts of" superdoers "reach remission rates twice as high as average" Our hope is that, if we can understand how this happens, we can improve the success of fecal transplantation and even test the procedure for new conditions badociated with the microbiome, such as Alzheimer's disease, multiple sclerosis and asthma. "

"

Jon Landy is a gastroenterologist in the network of hospitals serving the western region of Hertfordshire, England. It helps coordinate the transplant unit.

"We still do not understand what a super-charger is doing."

"We still do not understand what a super-charger is doing."

He is still in agreement with the idea of ​​a "super-charger". We certify that donors are healthy people with no disease, but we do not test the entire microbiome to see how it is. "

" These are investigations of this type that must be conducted. "

Fecal Bacteria

O. Sullivan's research, published in the scientific journal Frontiers in Cellular and Infection Microbiology, indicate that the presentation of a wide variety of microorganisms Fecal organisms could be an advantage.

According to him, the presence of a greater number of species in the feces of the donor has turned out to be one of the factors that most influence the outcome of fecal transplantation

But studies suggest that the success of the procedure may also depend on the donor's compatibility with the patient.

And it may be that is not just a question of "

" Some cases of recurrent diarrhea have been cured with filtered stool transplants, all living bacteria have been filtered but still contain DNA, viruses and at very debris. "

" viruses can affect the survival and metabolic function of bacteria and other grafted microbes, "says O. Sullivan.

Julie McDonald, a microbiologist at Imperial College London, UK, is studying ways to increase transplant recipients' success rates.

Currently, most donations are used to treat infections C lostridium difficile which may occur when the "good" bacteria in the patient's digestive tract are removed by antibiotics .

McDonald's research suggests that fecal transplants play a very specific role, replacing something that has been lost as a result of the disease.

She discovered that patients with C lostridium difficile showed almost imperceptible levels of a short-chain fatty acid valerate produced by microbial metabolism of healthy intestines.

Levels could only be restored with a well "

" In our laboratory, we try to find out exactly how grafts work and we find that even if we stop transplanting the stool itself. "

Instead of giving the patient a fecal injection, he would receive a treatment based on what could be considered less invasive."

According to her, this could help to get around the taboo problem badociated with d

Campenella wants people to "overcome the psychological barrier" and plan to become a donor

"Giving is very easy. It's easy to do. If you think about it, make sure that a nearby hospital offers the service and contact them. "

" I collect my new sample at home in a container provided by the hospital. And I leave the hospital on my way to work. It's just a small effort, "she adds.

She is now considering becoming a blood donor too.

" I have not donated yet, but Is something that I could do. "

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