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Women who go through the chemotherapy process may be a closer reality, according to a study by Danish scientists ( Photo: Thinkstock)
Read more Becoming a mother can freeze ovarian tissue before undergoing treatment. After healing, the tissues are reimplanted and they can regain their fertility naturally. But in some cases, such as ovarian tumors and leukemia, cancer cells can affect the ovary's own tissues. In these situations, there is a risk that the reimplantation will reappear the tumor, rendering the technique unsuitable.
At Rigshospitalet, a team led by Susanne Pors believes that "artificial ovaries" could be a safer option. . At a presentation Monday at the annual meeting of the European Society for Human Reproduction and Embryology in Barcelona, the researchers presented a technique that involves "creating" a new ovary.
With Chemical Agents, scientists removed all cells from the given ovarian tissue, including cancer cells. In the bare tissue, essentially collagenous, were implanted human follicles, small sacs that store the eggs until they are matured. In the laboratory, researchers implanted one of these "artificial ovaries" with 20 follicles in a mouse and, after three weeks, the blood vessels already provided the ovary inside the larynx. animal
– This is the first proof that. This is a milestone on a long road, "Susanne told the Guardian
Among the experts, the experiment was greeted with hope, but provided that clinical trials did not occur have been made to prove the effectiveness of the new technique. It is expected that the first human trials will take place within three to five years.
– The ability to create a "new ovary", by removing any tissue that can reintroduce cancer, allows the reimplantation of a safe ovary with the potential to successfully restore fertility, "said Adam Balen of the University of Ottawa. Seacroft Hospital in Leeds, England, not involved in research. "It's still a proof of concept, with human tissue transplanted into the mouse to demonstrate that the transplant can work but must undergo clinical trials."
The BBC, Stuart Lavery, a gynecologist at Hammersmith Hospital, said that compared to current in vitro fertilization treatments, allowing women to get pregnant "naturally". Gillian Lockwood, director of Midlands Fertility, notes that the implantation of follicles allows women to restart their menses, avoiding hormone replacement therapies.
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